Histopathological characteristics of small diameter melanocytic naevi

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Histopathological characteristics of small diameter melanocytic naevi.

BACKGROUND/AIMS The clinical definition of an atypical naevus ("dysplastic naevus" or "naevus with architectural disorder and cytological atypia of melanocytes") stresses size larger than 5 mm in diameter as a major diagnostic criterion. Because malignant melanomas and their precursors may arise in smaller lesions, a histological study of melanocytic lesions smaller than 4 mm in diameter was co...

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Congenital melanocytic naevi (CMN) are a known risk factor for melanoma, with the greatest risk currently thought to be in childhood. There has been controversy over the years about the incidence of melanoma, and therefore over the clinical management of CMN, due partly to the difficulties of histological diagnosis and partly to publishing bias towards cases of malignancy. Large cohort studies ...

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Spectrophotometric analysis of melanocytic naevi during pregnancy.

Malignant melanoma is the most common cancer during pregnancy, but it is unknown whether melanocytic naevi in general are activated. A total of 381 melanocytic naevi in 34 Caucasian primigravidae were examined using spectrophotometric intracutaneous analysis (SIAscopy) technology in early pregnancy and prior to delivery. The Siagraphs of each naevus were then compared in order to evaluate chang...

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Histopathological Correlates of the Parallel-Furrow Pattern Seen in Acral Melanocytic Naevi at Dermatoscopy

compound melanocytic naevus was made. The remaining portion of the lesion was used for transverse histological sectioning to reproduce the original dermatoscopic plan, as tissue sections were parallel to the skin surface ( fig. 2 b). The analysis of transverse sections showed several pigmented structures: types of melanin in the horny layer under the ridges, junctional and papillary nests of me...

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Relation between phenotype and banal melanocytic naevi.

In a study of risk factors for the development of melanocytic naevi in relation to the pathogenesis of malignant melanoma 197 white adults were examined by four dermatologists and naevus counts correlated with several other features. Highly significant associations were found between large numbers of banal acquired melanocytic naevi and the ability to tan easily without burning (skin types 3 an...

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ژورنال

عنوان ژورنال: Journal of Clinical Pathology

سال: 2003

ISSN: 0021-9746

DOI: 10.1136/jcp.56.6.459